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Job reference: BMH-021349
Location: Oxford Road
Closing date (DD/MM/YYYY): 28/02/2023
Salary: £34,308 to £35,333 per annum, depending on relevant experience
Employment type: Fixed Term
Faculty/Organisation: Biology, Medicine Health
Division: Division of Molecular and Cellular Funct
Hours Per Week: Full Time
Contract Duration: From 1 April for 12 months
School / Directorate: School of Biological Sciences
Based on the laboratory of Dr Christos Pliotas at the University of Manchester, you will work on an exciting project on dynamics and catalysis of integral membrane pyrophosphatases, aiming to determine how they pump both sodium ions and protons, to determine the mechanism (alternating or both ions pumped through a single chain at once) of this and of gate opening, and to use this as the basis for drug design. The project combines protein production and purification, subcellular trafficking and electrophysiological measurements to determine the molecular pathways as well as the structure of this challenging system.
You will be a highly motivated individual with a strong basis in cellular and structural biology, and experience in working with integral membrane proteins. You should have a PhD (or be close to completion) or equivalent in Molecular Biology, Biochemistry or a closely allied discipline and have previous experience in cloning, eukaryotic tissue culture, membrane protein expression and purification and/or electrophysiology. Experience in lipid assays and structural biology would be desirable.
The School/Department is strongly committed to promoting equality and diversity, including the Athena SWAN charter for gender equality in higher education. The School/Department holds a Silver Award which recognises their good practice in relation to gender; including flexible working arrangements, family-friendly policies, and support to allow staff achieve a good work-life balance. We particularly welcome applications from women for this post. All appointment will be made on merit. For further information, please visit: https://www.bmh.manchester.ac.uk/about/equality/
Our University is positive about flexible working – you can find out more here
Blended working arrangements may be considered
Please note that we are unable to respond to enquiries, accept CVs or applications from Recruitment Agencies.
Enquiries about the vacancy, shortlisting and interviews:
Name: Christos Pliotas
Email: [email protected]
General enquiries:
Email: [email protected]
Technical support:
https://jobseekersupport.jobtrain.co.uk/support/home
This vacancy will close for applications at midnight on the closing date.
